Staphylococcal Infections

نویسندگان

  • John S. Bradley
  • Victor Nizet
چکیده

Epidemiology and Transmission 487 Staphylococcus aureus 487 Coagulase-Negative Staphylococci 488 Microbiology 489 Staphylococcus aureus 489 Coagulase-Negative Staphylococci 490 Pathogenesis of Disease 490 Virulence Factors of Staphylococcus aureus 490 Epithelial Attachment and Invasion 490 Innate Immune Resistance 491 Secreted Toxins 492 Quorum Sensing and Regulation of Virulence Factor Expression 493 Virulence Mechanisms of Coagulase-Negative Staphylococci 493 Role of the Host Defenses 494 Pathology 495 Clinical Manifestations 495 Bacteremia and Sepsis 495 Toxic Shock Syndromes 497 Endocarditis 497 Pustulosis, Cutaneous Abscess, and Cellulitis 498 Adenitis and Parotitis 498 Breast Infection 498 Funisitis, Omphalitis, and Necrotizing Fasciitis 498 Staphylococcal Scalded Skin Syndrome and Bullous Impetigo 500 Pneumonia 500 Meningitis 502 Brain Abscess 502 Osteoarticular Infection 502 Infections of the Gastrointestinal Tract 503 Diagnosis 503 Antibiotic Treatment 504 General Principles 504 Vancomycin 504 Clindamycin and Erythromycin 505 Linezolid 505 Daptomycin 506 Quinupristin-Dalfopristin 506 Combination Antimicrobial Therapy 506 Catheter Removal 506 Prevention 507 Hygienic Measures 507 Antibiotic Prophylaxis 507 Immunoprophylaxis 507 Conclusion 508

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تاریخ انتشار 2010